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相关临床试验
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药物批准
3
批准总数
监管机构
2
监管机构数
成立时间
N/A
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NMPA
National Medical Products Administration
1
FDA
Food and Drug Administration
- Real-world data shows belumosudil is often used in combination after multiple prior therapies for chronic graft-versus-host disease (cGVHD). - A retrospective study in Germany and Switzerland found a 42% overall response rate in patients with advanced cGVHD treated with belumosudil. - Belumosudil demonstrated a steroid-sparing effect and manageable safety profile in patients with severe cGVHD. - The ROCK2 inhibitor shows potential in earlier lines of cGVHD therapy, warranting further investigation in prospective trials.