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相关临床试验
37
8 进行中
药物批准
0
批准总数
监管机构
监管机构数
成立时间
1931
进行中（未招募）
5
13.5%
已完成
23
62.2%
尚未招募
3
8.1%
招募中
6
16.2%
暂无批准数据
- A randomized controlled trial of 32 dogs with canine cognitive dysfunction demonstrated that a single intramuscular injection of long-acting donepezil depot significantly improved behavioral scores and reduced serum neurofilament light chain levels. - High-dose treatment showed significant improvements in cognitive assessment scales at both 14 and 28 days, while low-dose treatment primarily improved at day 28 with earlier effects limited to one scale. - Both treatment groups had significantly lower serum NfL levels than controls at day 28, with quality-of-life improvements in activity, sociability, and overall condition. - The study highlights the potential for integrating clinical and biomarker-based assessments in future canine cognitive dysfunction management, with adverse events being mild and transient.
