相关临床试验
1
1 进行中
药物批准
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监管机构
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成立时间
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进行中（未招募）
1
100.0%
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- A Nature study presents the first genomic analysis of eight Myotis bat species, linking longer lifespans to stronger immune defense and cancer-suppressing gene activity. - Cells from the little brown bat responded to lethal chemical damage by activating cell-death genes rather than DNA repair, mirroring the elephant's anti-cancer strategy. - Researchers found far more overlap than expected by chance between genes associated with bat longevity and genes involved in bat-virus interactions. - Myotis bats show unusual enrichment of genes interacting with DNA viruses such as herpesviruses, a pattern opposite to humans and other primates.
- Researchers at University of Pittsburgh and Penn State developed a novel "trans-amplifying" mRNA vaccine platform that requires 40 times less mRNA than conventional vaccines while maintaining robust immune responses. - The innovative approach separates mRNA into two fragments, allowing the replicase sequence to be produced in advance and significantly reducing vaccine development time and production costs. - The vaccine uses a consensus spike protein design that demonstrated broad protection against multiple SARS-CoV-2 variants in mouse studies, potentially eliminating the need for frequent updates. - The platform shows promise for application to other rapidly evolving RNA viruses with pandemic potential, including H5N1 avian influenza.
