相关临床试验
274
49 进行中
药物批准
0
批准总数
监管机构
0
监管机构数
成立时间
N/A
进行中(未招募)
6
2.2%
已完成
79
28.8%
Enrolling By Invitation
2
0.7%
尚未招募
41
15.0%
招募中
64
23.4%
暂停
1
0.4%
终止
3
1.1%
Unknown
72
26.3%
撤回
6
2.2%
暂无批准数据
- A crossover randomized controlled trial, DBS-HITS, is investigating deep brain stimulation (DBS) of the hippocampus for treatment-resistant schizophrenia. - The study involves six participants with chronic, treatment-resistant schizophrenia undergoing DBS surgery and subsequent stimulation parameter optimization. - Participants will be randomized to receive either high-frequency stimulation or sham stimulation for three months each, with blinded evaluations. - The primary outcome is the comparison of response rates in PANSS total, positive, and negative scores, with secondary outcomes including cognitive and neuroimaging changes.
- Chinese scientists report cognitive improvements in an Alzheimer's patient following lymphatic venous anastomosis (LVA) surgery, a novel approach to enhance brain waste clearance. - The LVA procedure connects neck lymphatic vessels to veins, aiming to facilitate the removal of harmful beta-amyloid and tau proteins from the brain. - Initial results showed improvements in cognitive function tests and a reduction in depression symptoms five weeks post-surgery in a 76-year-old patient. - Researchers emphasize the need for broader studies to confirm these findings, while noting the potential of LVA as a new direction in Alzheimer's treatment research.