相关临床试验
32
3 进行中
药物批准
0
批准总数
监管机构
0
监管机构数
成立时间
1965
已完成
21
65.6%
尚未招募
3
9.4%
招募中
3
9.4%
暂停
1
3.1%
终止
2
6.3%
Unknown
2
6.3%
暂无批准数据
- Simon Fraser University researchers published a new method in *Science* that uses a light-driven reaction to rapidly generate large libraries of nucleoside analogs from a single scalable building block. - The approach can produce compound libraries 10 to 100 times larger in weeks rather than months or years, dramatically accelerating early-stage antiviral drug discovery. - Screening the library against HIV identified three compounds with activity comparable to approved HIV therapies, with most compounds being entirely new. - The research, conducted in collaboration with scientists at Merck, addresses a critical gap in antiviral drug development amid emerging viral threats like COVID-19, Ebola, and hantavirus.
- Simon Fraser University researchers used advanced MEG brain imaging to discover why levodopa, the primary Parkinson's drug, works differently across patients. - The study found that levodopa sometimes activates unintended brain regions, creating "off-target" effects that reduce the drug's therapeutic benefits. - This breakthrough could enable personalized treatment approaches by allowing clinicians to visualize how levodopa affects individual patients' brain activity. - The research involved 17 Parkinson's patients and represents a collaboration between SFU and Sweden's Karolinska Institute.
