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- An 11-year-old Tucson boy, Giovanni "Gio" Cruz, was diagnosed with idiopathic multicentric Castleman disease after sudden chest and back pain that began in June. - The rare immune disorder affects roughly three Americans per million, causing lymph nodes to enlarge throughout the body and triggering widespread inflammation that can damage organs. - Gio is currently receiving IL-6-directed therapy, high-dose IV steroids, and dialysis, with chemotherapy considered if he does not respond. - The cause of the disease is unknown, and it can affect organs including the liver, kidneys, and bone marrow.