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- Researchers developed namiRa by systematically curating 9,983 scientific publications, integrating experimentally validated data on 1,095 human miRNAs across 33 cancer types. - The database provides multi-layered evidence including miRNA expression patterns, functional characterization from in vitro and in vivo studies, validated target genes, and interactive regulatory network visualization. - namiRa aims to accelerate cancer biomarker discovery, therapeutic target identification, and data-driven precision medicine research. - The study was published in Computers in Biology and Medicine (Elsevier) and the database is freely accessible at www.namira-db.com.
- Scientists at the University of Duisburg-Essen have developed an automated method to grow lung organoids, reducing manual labor and increasing production capacity for drug testing applications. - The automated bioreactor system successfully produced lung organoids with airway and alveolar features comparable to manually grown versions, though with some structural differences including larger size and fewer alveolar spheres. - This breakthrough could enable personalized medicine approaches by allowing clinicians to test therapies on patient-specific "mini lungs" grown from individual cells, potentially transforming respiratory disease treatment development. - While current organoids lack some cellular components like immune cells and blood vessels, researchers believe the technology shows promise for patient-oriented screening platforms despite requiring further optimization.