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- Jennifer Hunt officially begins her tenure as dean of Dartmouth's Geisel School of Medicine, becoming the first woman to lead the institution in its 229-year history. - Hunt joins from the University of Florida College of Medicine, bringing decades of experience as an internationally recognized pathologist and physician-scientist with over 160 peer-reviewed publications. - On her first days, Hunt welcomed incoming MD and MPH students, emphasizing the importance of entering health sciences at a crucial time for the nation's healthcare system. - Hunt succeeds interim dean Steven Leach, who described Geisel as "strong and thriving," with a $100M sponsored research portfolio and successful completion of a $50M fundraising goal for the Dartmouth Cancer Center.
- Researchers at the University of Florida have discovered that NSD2 overexpression in multiple myeloma cells leads to secretion of factors that suppress MHC class II molecules on immune cells, potentially enabling tumor immune evasion. - NSD2, a histone methyltransferase frequently overexpressed in patients with t(4;14) translocation, affects cell metabolism and alters metabolite secretion patterns that may inhibit immune system function. - The research team is developing mouse models to validate their in vitro findings, with plans to test selective NSD2 inhibitors as potential therapeutic agents to restore immune function and enhance antitumor responses.
