相关临床试验
29
5 进行中
药物批准
0
批准总数
监管机构
0
监管机构数
成立时间
1842
进行中（未招募）
3
10.3%
已完成
10
34.5%
Enrolling By Invitation
1
3.5%
尚未招募
1
3.5%
招募中
7
24.1%
Unknown
2
6.9%
撤回
5
17.2%
暂无批准数据
- The FDA approved Evita Solutions' generic version of mifepristone in September, sparking controversy among lawmakers and pro-life advocates. - Senate Health, Education, Labor and Pensions Committee held a contentious hearing examining the safety protocols for mifepristone distribution. - Republican senators called for restoration of in-person dispensing requirements, while Democrats defended the drug's safety profile. - FDA Commissioner Marty Makary faces criticism for allegedly slow-walking a comprehensive safety review of mifepristone.
- The World Health Organization has issued its first recommendation for a new malaria vector control tool in over 40 years, endorsing spatial repellents that provide an average 56% protection against mosquito bites. - Clinical trials funded by Unitaid demonstrated that spatial repellents reduced malaria cases by one-third when used alongside insecticide-treated nets, leading to WHO's conditional recommendation in August. - Three spatial repellent products are now available, with Guardian offering up to one year of protection, addressing critical gaps as traditional vector control methods face declining effectiveness due to insecticide resistance. - Unitaid has launched an $18 million investment to expand evidence for spatial repellents as standalone interventions, particularly important as global funding cuts make layering multiple interventions increasingly unaffordable.
- Researchers have discovered that nitisinone, a drug used to treat rare genetic disorders, makes human blood toxic to mosquitoes that transmit malaria, offering a potential new control strategy. - The study published in Science Translational Medicine demonstrated nitisinone remains active in bloodstream longer than current alternative ivermectin and effectively kills mosquitoes of all ages, including those resistant to traditional insecticides. - Nitisinone works by blocking the HPPD enzyme in mosquitoes, preventing them from digesting blood and causing rapid paralysis and death, potentially providing an alternative in regions with ivermectin resistance.
