相关临床试验
1369
409 进行中
药物批准
0
批准总数
监管机构
0
监管机构数
成立时间
1096
终止
42
3.1%
招募中
115
8.4%
暂停
10
0.7%
撤回
13
0.9%
进行中（未招募）
360
26.3%
已完成
692
50.5%
Unknown
87
6.4%
Enrolling By Invitation
9
0.7%
尚未招募
40
2.9%
暂无批准数据
- The 2026 Ig Nobel Prizes were awarded on 3 September at a ceremony in Zurich, Switzerland, marking the first time in 36 years the event was held outside Boston. - The Chemistry prize recognized researchers who found cockroach milk proteins contain three times more energy than cow's milk proteins, using an X-ray free-electron laser. - The Biomechanics prize honored a team that defined kissing as non-agonistic oral–oral contact without food transfer, tracing the behavior back roughly 21.5 million years. - The Soil Science prize went to University of Zurich researchers who enlisted citizen scientists in over 25 nations to bury and later dig up 1,000 pairs of underwear to gauge soil health.
- The Nuffield Department of Medicine at the University of Oxford and 2U have launched a six-week online executive education program focused on applying artificial intelligence across the drug discovery pipeline. - The Oxford AI in Drug Discovery and Medicine Programme equips scientists, researchers, and R&D professionals with AI skills spanning target identification, biomarker discovery, patient stratification, and therapeutic prediction. - The curriculum integrates ethical, legal, and regulatory considerations, including algorithmic bias, model explainability, and responsible deployment, with no coding experience required. - The partnership expands 2U's relationship with the University of Oxford to more than 40 online programs, with a second NDM offering in healthcare management expected later this year.
- Mirae, an AI-driven continuous care platform for autoimmune disease and complex chronic conditions, announced $5.4 million in funding led by Oxford Science Enterprises. - The University of Oxford spinout builds on research from the Computational Health Informatics Lab, with an initial focus on inflammatory bowel disease (IBD). - The platform converts everyday patient-reported signals into a structured, longitudinal view of disease to support earlier detection and more informed treatment decisions. - Chronic disease could cost the U.S. up to $47 trillion over the next 15 years, underscoring the need for continuous, data-driven care beyond episodic visits.
- A University of Oxford study analyzing nearly 2,800 bacterial genomes across 30 countries found industrial poultry farming has caused a more than 100-fold increase in Campylobacter movement between wild birds and commercial flocks. - Campylobacter jejuni is the leading bacterial cause of foodborne gastroenteritis worldwide, causing 1.9 million illnesses and 13,000 hospitalizations in the U.S. in 2019 alone. - Genomic analysis revealed genetic adaptations in the bacterium linked to antimicrobial resistance, oxidative stress tolerance, and enhanced survival in modern production systems. - Researchers call for poultry industry to adopt coordinated biosecurity and vaccination strategies similar to those used against Salmonella to curb the growing public health threat.
- The HyPrevent platform has assembled a deeply phenotyped longitudinal cohort of over 3,600 participants to study how hypertension during pregnancy affects the heart, brain, and blood vessels across the life course. - Researchers developed a unified global organ-damage risk score (HyperScore) and identified distinct disease progression pathways (HyperTrajectories) linked to mortality and advanced organ damage. - The Lapidaire Group investigates postpartum brain and microvascular changes using multimodal imaging and a novel portable device (VITA) to detect early cerebrovascular and microvascular alterations. - Findings aim to inform better prevention and management strategies, with integration into a clinical postnatal hypertension service and the ongoing FLOWER study at Oxford University Hospitals.
- The Phase II GALAXY study found ctDNA testing after surgery for colorectal liver metastases strongly predicts which patients benefit from adjuvant chemotherapy. - Among ctDNA-positive patients who had upfront surgery, adjuvant chemotherapy was associated with 65% vs 33% four-year overall survival and a 93% reduction in recurrence risk. - Patients without detectable ctDNA had favorable outcomes regardless of adjuvant chemotherapy, suggesting the test could spare some from unnecessary treatment. - Experts caution that randomized trials are still needed before ctDNA-guided treatment decisions become standard practice outside clinical trials.
- The University of Oxford and The Little Princess Trust have established a £5.25 million partnership to expand rare paediatric cancer research at the Oxford-Harrington Rare Disease Centre. - Professor Isidro Cortés-Ciriano has been appointed the first Little Princess Trust Professor of Paediatric Oncology to lead a new childhood cancer research programme within Oxford's Department of Paediatrics. - Professor Cortés-Ciriano will provide scientific leadership for the OHC Cancer Theme, integrating computational cancer genomics, AI, and drug development expertise across Oxford and Cleveland. - Childhood cancer remains a leading cause of disease-related death in children worldwide, with approximately 20,000 children and young people diagnosed annually in the UK and US combined.
- Experts at a Hindu webinar emphasized urgent need for better lab infrastructure, healthcare worker training, and data sharing to prepare for the next pandemic. - Contact tracing, community engagement, and dignified patient burials were highlighted as critical lessons from the Ebola outbreak in the Democratic Republic of Congo and Uganda. - The WHO and University of Oxford experts stressed that countries including India must adopt the One Health Approach and strengthen disease surveillance systems. - Clinicians warned against antibiotic self-medication, citing its role in the growing antimicrobial resistance crisis, and called for government data analytics to help anticipate outbreaks.
- A pilot trial found that daily spermidine supplementation improved antibody responses to COVID-19 vaccination in older adults who previously responded poorly. - About one quarter of participants aged 65 and older showed weak antibody responses despite three vaccine doses, with immune cells displaying signs of biological aging. - Spermidine reduced markers of immunosenescence and stimulated autophagy, the cellular recycling process that declines with age. - The supplement was safe and well tolerated, but larger studies are needed to confirm effects across other vaccines such as seasonal influenza.
- Patient and public involvement (PPI) is now a mandatory requirement for most UK medical research funders, including detailed PPI plans in grant applications. - Basic, preclinical, and laboratory-based research presents unique PPI challenges due to its distance from patient lived experience, yet offers significant benefits for research relevance. - Experts argue that evaluating the PPI process is as important as measuring its impact, emphasizing continuous improvement and meaningful engagement over simple justification. - Researchers should use frameworks like the UK Standards for Public Involvement and provide feedback to public contributors to ensure they feel valued and motivated.
