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- The American Red Cross has declared an emergency blood shortage, with the national blood supply falling to just 25% of what is needed, marking only the second such crisis declaration in its history. - Type O positive blood reserves have dropped to less than a one-day supply, forcing the organization to limit hospital distributions to only the most critical, life-threatening emergencies. - Summer trauma cases, including a 65% increase in fireworks-related injuries at one major medical center, are driving demand while donations decline due to school closures, vacations, and extreme weather. - The Red Cross estimates that just three additional donors at each blood drive this summer could help stabilize the national blood supply.
- The TRACTION trial demonstrated that tranexamic acid reduced the need for red blood cell transfusions by 31% in patients undergoing high-risk non-cardiac surgeries compared to placebo. - Among 8,273 patients across 10 Canadian hospitals, tranexamic acid lowered transfusion rates from 9.8% to 7.4% without increasing venous thromboembolism risk. - The findings suggest broad implementation could prevent 5-10 million units of perioperative red cell transfusions annually in the estimated 100 million non-cardiac surgeries performed yearly. - The inexpensive, widely available drug showed particular safety in cancer patients, who comprised 60.5% of the study population and face elevated thrombosis risk.