EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

计划入组 160 人 · 首次发布于 2025 年 12 月 3 日

First-in-Human Study of ATX-559, an Oral Inhibitor of DHX9, in Patients With Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers

计划入组 17 人 · 首次发布于 2024 年 10 月 3 日

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

计划入组 14 人 · 首次发布于 2024 年 11 月 29 日

helicase inhibitors (Microbiotix)

Helicase inhibitors(Boehringer Ingelheim/Epizyme)

Pol Theta Helicase Inhibitor (IDEAYA/GSK)

IDEAYA Biosciences' Werner Helicase Inhibitor IDE275 Cleared for Phase 1 Trial in MSI-High Solid Tumors

Assembly Biosciences Initiates Phase 1b Trial of Long-Acting HSV Helicase-Primase Inhibitor ABI-1179

MOMA Therapeutics Initiates First-in-Human Trial of Werner Helicase Inhibitor MOMA-341 for MSI-H Solid Tumors