Changes in salt perception as a result of a long-term salt reduced diet

Completed

• Conditions: preferentie voor zout; salt perception and salt preference; 10019280; 10057166

• Registration Number: NL-OMON35225
• Lead Sponsor: Wageningen Universiteit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

Inclusion criteria for the intervention group of the *Salt* study:
- Participation in the Ka/Na-trial
- Willing to participate in the *Salt* study;Inclusion criteria for the control group of the *Salt* study:
- Drop-outs of Ka/Na-trial due to a too low blood pressure (SBP < 130 mm Hg)

Exclusion Criteria

Exclusion criteria intervention and control group of the Salt study (only for MRI measurements, there are no exclusion criteria for sensory tests):
• Having a contra-indication to MRI scanning:
(claustrophobia, epilepsy, serious physical or mental illnesses, pacemakers and defibrillators, intraorbital or intraocular metallic fragments, difficulties eating and or swallowing)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Brain activity in reward area's<br /><br>Saltiness preference (subjective ratings)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Sensitivity for saltiness, measured by:<br /><br>-threshold NaCl<br /><br>-Supra threshold subjective ratings of NaCl in water<br /><br><br /><br>Desire-to-eat salty foods (subjective ratings)</p><br>