Effect of lubiprostone on CKD patients to protect renal functio
Not Applicable
Recruiting
- Conditions
- chronic kidney disease
- Registration Number
- JPRN-UMIN000023850
- Lead Sponsor
- Tohoku Univerisy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
Not provided
Exclusion Criteria
1, inflammmatry diseases 2, oral absorbent 3, PSL more 5mg , immunosuppressant 4, oral absorbent 5, ARF 6, Drug-induced renal failure 7, renal transplant 8, RRT 9, gut obstruction 10, sensitive for lubiprostone 11, symptomatic constipation 12, diarrea 13, gut diesases 14, abdominal operation within 6 mo 15, HbA1c>9% 16, BP > 160/90 17, serious heart, liver, kidney, lung, CNS diseases 18, malignancy 19, unable for contraception 20, other clinical study enrollment within 3mo 21, exacerbation of lab data during screening 22, Can not follow instruction 23, Inadequate for trial
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of concentration of serum indoxyl sulfate before and after administration
- Secondary Outcome Measures
Name Time Method