MAYO CLINIC

A comprehensive analysis of 19 clinical trials involving 6,506 patients found tramadol provides only minimal pain relief that falls below clinically meaningful thresholds for chronic pain management.

Ryght AI announces formation of inaugural Scientific Advisory Board comprising 12 globally recognized experts in oncology, hematology, dermatology, and AI to guide clinical trial innovation.

Two major clinical trials presented at ASTRO 2025 reached opposite conclusions about proton beam therapy's effectiveness compared to intensity-modulated radiotherapy (IMRT) for head and neck cancer treatment.

Leo Cancer Care launched Grace™, the first upright photon therapy system, at ASTRO 2025, challenging conventional horizontal radiation therapy approaches.

Lutetium Lu 177 dotatate demonstrated antitumor activity in patients with metastatic bronchopulmonary neuroendocrine tumors, achieving partial responses in 17% of patients in a real-world study.

A 9-year-old golden retriever with metastatic oral melanoma achieved complete tumor remission after participating in a clinical trial testing inhaled IL-15 immunotherapy at UC Davis.

A Mayo Clinic phase 3 trial demonstrates that de-escalated adjuvant radiation therapy (DART) significantly reduces severe toxicity rates from 11% to 3% compared to standard treatment in HPV-positive oropharyngeal cancer patients.

A custom-built antisense oligonucleotide drug targeting the CHCHD10 gene mutation has slowed ALS progression by more than half in Dr. Rakesh Parekh, marking the first treatment for this specific genetic variant.

TREOS Bio has initiated OBERTO-202, a potentially registration-enabling Phase II trial evaluating PolyPEPI1018 combined with toripalimab and standard care in 140 patients with microsatellite stable metastatic colorectal cancer.

Arctx Medical received FDA Investigational Device Exemption approval to conduct a pivotal clinical trial of its Cool Catheter Kit in approximately 200 acute pancreatitis patients at up to 25 US hospitals.