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Clinical Trials/NCT05071560
NCT05071560
Completed
N/A

Pilot Study of Supervised Adapted Physical Exercise in Women With Breast Cancer After Treatment - Face-to-face Context vs Online Home Based

Associacao de Investigacao de Cuidados de Suporte em Oncologia1 site in 1 country12 target enrollmentMay 1, 2021
ConditionsBreast Cancer

Overview

Phase
N/A
Intervention
Not specified
Conditions
Breast Cancer
Sponsor
Associacao de Investigacao de Cuidados de Suporte em Oncologia
Enrollment
12
Locations
1
Primary Endpoint
Retention rate
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The present investigation is a pilot feasibility study that aims to compare a physical exercise intervention in a face-to-face context (considered state of the art) with a physical exercise intervention in a distance context (online), both supervised, in women, of legal age, physically inactive, breast cancer survivors after primary treatment with curative intent.

Before and after the intervention these women will have a physical and functional assessment, as well as a pre-trial cardiopulmonary exercise test, to check if there are safety conditions to participate and also to self tailor the exercise prescription.

The prescription follows the ACSM´s exercise guidelines for cancer survivors and will comprise a 8 week combined exercise training, 3 times per week, in which two of them will be supervised and the third session of the week (cardio session) won´t.

Chat´s and weekly personal messages, as well as education, will be used to promote retention and exercise adherence.

Registry
clinicaltrials.gov
Start Date
May 1, 2021
End Date
September 30, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Associacao de Investigacao de Cuidados de Suporte em Oncologia
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Over legal age
  • With diagnosis of breast carcinoma between stages 0 and IIIc
  • ECOG 0 to 1
  • Undergoing primary treatment with curative intent (surgery associated or not, with chemotherapy and / or adjuvant radiotherapy) for at least one month
  • With follow-up on medical oncology consultation at CHVNG/E
  • With consent of the attending oncologist for the practice of physical exercise
  • Non-compliance with current physical activity guidelines recommended by the ACSM (moderate aerobic activity\> = 150 min / week or vigorous\> = 75 min / week and \> = 2 strength training sessions / week)
  • With cognitive capacity to understand the project proposal

Exclusion Criteria

  • Severe anaemia seen in the last 3 months (Hb \<= 8g / dl) or moderate (Hb\> 8 and \<= 10 g / dl) symptomatic (sustained tachycardia, exertional dyspnea, chest pain or syncope),
  • Uncontrolled arterial hypertension (HTN grade 3-4 (CTCAE v.5)) (SAD\> = 160mmHg and / or DAD\> = 100mmHg) and / or potentially fatal consequences (malignant HTN, transient or permanent neurological deficit or hypertensive crisis)
  • Uncontrolled diabetes mellitus
  • Known cardiac or respiratory pathology
  • Any other contraindication given by the physiatrist and / or assistant surgeon

Outcomes

Primary Outcomes

Retention rate

Time Frame: End of the intervention (week 9)

The percentage of included patients who ended the program

Adherence rate

Time Frame: End of the intervention (week 9)

Number of absences to the sessions and number of completed sessions

Training tolerance regarding the duration of the exercise prescription

Time Frame: During all intervention sessions (24 sessions, 8 weeks)

Recording adherence to the exercise prescription duration, possible adjustments and their reasons

Training tolerance regarding the intensity of the exercise prescription

Time Frame: During all intervention sessions (24 sessions, 8 weeks)

Recording adherence to the exercise prescription intensity, possible adjustments and their reasons

Training tolerance regarding the volume of the exercise prescription

Time Frame: During all intervention sessions (24 sessions, 8 weeks)

Recording adherence to the exercise prescription volume, possible adjustments and their reasons

Intervention Recruitment Rate

Time Frame: Beginning of the intervention (week 0)

Number of invitations made versus accepted (invitation made by the assistant oncologist)

Training safety

Time Frame: During all intervention sessions (24 sessions, 8 weeks)

Recording symptoms and adverse effects

Absence and dropout

Time Frame: End of the intervention (week 9)

Rate of absence from sessions and dropout of the program

Level of satisfaction

Time Frame: End of the intervention (week 9)

Questionnaire at the end of the intervention, from 1 to 5, where 1 is not satisfied and 5 is very satisfied

Secondary Outcomes

  • Cardiopulmonary system fitness level and signs of disease assessment(Beginning of the intervention (week 0))
  • Lower limb strength(Beginning (week 0) and End of the intervention (week 9))
  • Upper limb strenght(Beginning (week 0) and End of the intervention (week 9))
  • Lower limbs flexibility level(Beginning (week 0) and End of the intervention (week 9))
  • Static balance(Beginning (week 0) and End of the intervention (week 9))
  • Dynamic balance and agility(Beginning (week 0) and End of the intervention (week 9))
  • Assessment of aerobic capacity(Beginning (week 0) and End of the intervention (week 9))
  • Safety of the intervention(During all intervention sessions (24 sessions, 8 weeks))
  • Body weight(Beginning (week 0) and End of the intervention (week 9))
  • Body height(Beginning (week 0) and End of the intervention (week 9))
  • Body circumferences(Beginning (week 0) and End of the intervention (week 9))
  • Individual's overall satisfaction with life and general sense of personal well-being(Beginning (week 0) and End of the intervention (week 9))
  • Individual's overall satisfaction with life and general sense of personal well-being, specific to breast cancer patient(Beginning (week 0) and End of the intervention (week 9))
  • Adverse effects(During all intervention sessions (24 sessions, 8 weeks))
  • Assessment of performance status(During all intervention sessions (24 sessions, 8 weeks))
  • Heart Function(Beginning of the intervention (week 0))
  • Arterial disorder assessment(Beginning of the intervention (week 0))
  • Physical activity and sedentary behaviors(Beginning (week 0) and End of the intervention (week 9))
  • Subjective perception of effort(During all intervention sessions (24 sessions, 8 weeks))

Study Sites (1)

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