Exercise Training is a Feasible and Active Complementary Therapy in Adult and Elderly Patients Receiving Anti- Lymphoma Treatments
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Elderly Lymphoma Patients
- Sponsor
- University of Roma La Sapienza
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- The eligibility rate
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
This pilot study was designed in a real-life setting to establish the feasibility, the safety and the activity of a supervised and combined Exercise Training (ET) program in adult and elderly lymphoma patients undergoing cancer-treatments.
Detailed Description
Eligible patients were assigned to the ET group. All the patients eligible for exercise but not partiticpating to the ET program because of logistical reasons, were considered as the control group. All clinical outcomes were assessed before exercise training (T0), 3 (T1) and 6-months (T2) after the beginning of the exercise.
Investigators
Mario Vetrano, MD
MD, PhD
University of Roma La Sapienza
Eligibility Criteria
Inclusion Criteria
- •≥18-80 years old, histologically confirmed HL or NHL, patients in need of first or subsequent lines of systemic treatment and with a long-life expectancy
Exclusion Criteria
- •Patients were excluded if they had less than 4 months of anti-cancer treatment to be delivered, severe orthopaedic, cardiac, pulmonary, or cognitive impairment, osteolytic lesions with the risk of fracture, cachexia or if they were ≥ 65 years and frail on the basis of comprehensive geriatric assessment
Outcomes
Primary Outcomes
The eligibility rate
Time Frame: 6 months
the eligibility rate was assessed by the number of eligible patients divided by the total number of elements on the sampling frame.
Safety of the exercise training
Time Frame: 6 months
Safety was assessed by monitoring any serious adverse events that occured during the ET period.
The recruitment rate
Time Frame: 6 months
the recruitment rate was assessed by the number of patients included in the study divided by the total number of eligible patients
The exercise adherence rate
Time Frame: 4 months
The exercise adherence rate was assessed by the number of exercise sessions attended out of the 48 sessions scheduled for each patient
The assessment rate
Time Frame: 6 months
The assessment rate was assessed by the number of patients who completed the T1 and T2 follow-up times over the total number who participated in the study