Exercise Training Effect on Quality of Life and Exercise Capacity in Patients With Heart Failure and Preserved Ejection Fraction: A Pilot Study

MultiCare Health System Research Institute1 site in 1 country16 target enrollmentNovember 2015

ConditionsHeart Failure

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Heart Failure
Sponsor: MultiCare Health System Research Institute
Enrollment: 16
Locations: 1
Primary Endpoint: Change in Quality of Life (QOL) score pre and post exercise training (ET).
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this is to develop and implement a pilot study that will demonstrate the ability to recruit, enroll, retain, conduct exercise training, and collect pre and post outcomes on the effect of exercise training on quality of life (QOL) and exercise capacity in patients with a diagnosis of heart failure with preserved ejection fraction (HFPEF).

Registry

clinicaltrials.gov

Start Date

November 2015

End Date

January 2017

Last Updated

9 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

MultiCare Health System Research Institute

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age \> 55 years (Interested in capturing mean ages close to age 65 as many HF initiatives are based on this age group and HF development increases with aging).
•Diagnosis of HFPEF stable NYHA Stage II- III with an EF of ≥ 45%
•Stabilized on cardiac medications and post hospitalization \> 4 weeks
•Ability to participate in exercise testing and training.
•Referral from Cardiologist or primary care physician.

Exclusion Criteria

•Unstable Angina
•Uncontrolled diabetes
•Moderate to severe aortic stenosis
•Uncontrolled hypertension Systolic BP\>150 mm Hg or Diastolic BP \>100 mm Hg
•Valvular heart disease
•Untreated coronary artery stenosis \>50%
•Arrhythmias
•Pulmonary disease/COPD
•Dementia or cognitive impairment
•VAD or Transplant planned in next 6 months.

Outcomes

Primary Outcomes

Change in Quality of Life (QOL) score pre and post exercise training (ET).

Time Frame: 9 weeks

Secondary Outcomes

Change in exercise capacity/tolerance pre and post ET using Cardiopulmonary Exercise Testing.(9 weeks)
Demonstrated ability to coordinate patient transition from clinic to home or YMCA partnership based exercise program with weekly staff follow-up within the study timeline.(9 weeks)
Capture 90 day hospital readmission data starting with study enrollment date and within the participants' study timeline.(90 days)