Fatigability and Physical Performance: Effects of Resistance Training Variables Manipulation

Not Applicable

• Conditions: Aging
• Interventions: Other: Resistance training, LL; Other: Resistance training, HVHL; Other: Resistance training, HL; Other: Control group, CG

• Registration Number: NCT03619070
• Lead Sponsor: Universidade Federal do Triangulo Mineiro

Brief Summary

This study evaluate whether resistance training variables modulate the fatigability (power-duration relationship) and physical performance in adults and older adults

Detailed Description

The resistance training variables manipulation is utilized for maximize the results of resistance training. However it is unclear whether the resistance training variables manipulation modulates the fatigability (i.e. power-duration relationship) and whether this explains the improvement on physical performance (i.e. gait speed, sit-to-stand and timed up and go tests).

Study Timeline

• Study Start: 2018-05-20
• Status Verified: 2018-08
• Study First Submitted: 2018-08-01
• Study First Submitted QC: 2018-08-01
• Last Update Submitted: 2018-08-06
• Study First Posted: 2018-08-07
• Last Update Posted: 2018-08-08
• Primary Completion: 2018-09-30
• Study Completion: 2018-11-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

• Postmenopausal women (>12 months amenorrhea) with age above or equal 50 years old.
• No hormone therapy or phytoestrogens

Exclusion Criteria

• No-drinker alcohol (no alcohol intake whatsoever in their diet);
• Non- smokers;
• Hypertensive with uncontrolled blood pressure values;
• Diabetic with uncontrolled glycemia;
• Presence of arthropathies;
• Presence of myopathies;
• Skeletal musculotendinous disorder.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Lower load resistance training (LL)	Resistance training, LL	In the LL group, postmenopausal women will perform the resistance training with moderate volume (i.e. three sets per exercise performed until or close to failure) and low load (i.e. 30% of 1RM)
Higher volume resistance training (HVHL)	Resistance training, HVHL	In the HVHL group, postmenopausal women will perform the resistance training with high volume (i.e. six sets per exercise performed until or close to failure) and high load (i.e. 80% of 1RM)
Higher load resistance training (HL)	Resistance training, HL	In the HL group, postmenopausal women will perform the resistance training with moderate volume (i.e. three sets per exercise performed until or close to failure) and high load (i.e. 80% of 1RM)
Control group, (CG)	Control group, CG	In CG, the postmenopausal women group will not perform exercise

Primary Outcome Measures

Name	Time	Method
Fatigability	Changes in fatigability measure (e.g. baseline and after 12 weeks of intervention)	The fatigability will be evaluate by 60 maximum voluntary isometric contractions (3 s contraction, 2 s rest) in knee extensors at 70 degree.

Secondary Outcome Measures

Name	Time	Method
Physical Performance	Changes in physical performance measure (e.g. baseline and after 12 weeks of intervention)	The physical performance will be evaluate by gait speed tests (e.g. 10m walking at usual and fast pace, 400m walk at usual and fast pace).

Trial Locations

Locations (1)

Post-degree program in physical education; 🇧🇷 Uberaba, MG - Minas Gerais, Brazil