Physical functioning, fatigability, and their relation with recovery in acutely hospitalized older medical patients

Recruiting

Conditions: kwetsbaarheid, veroudering
fatigability
fatigue

Registration Number: NL-OMON48844

Lead Sponsor: centrum voor ouderengeneeskunde

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 200

Inclusion Criteria

aged 70 years or older;
willing to participate
medically able to participate
providing informed consent.

Exclusion Criteria

1. no understanding of the Dutch language;
2. lack of decision making capacity, due to:
a.previously diagnosed dementia;
b. delirium or other conditions that influence decision making capacity;
3. hospital admission for more than 48 hours, due to:
a.transfer from another hospital to the UMCG;
b.transfer from another ward (e.g. Intensive Care Unit (ICU), or rehabilitation
center) to an internal medicine ward in the UMCG;
4. expected stay in hospital for less than 48 hours or when the patient is
expected to die within <48 hours;
5. any medical condition that prevents the patient to safely participate in
assessments that require light physical activities.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>main study parameters are repeated measurements of mobility (assessed by De<br /><br>Morton Mobility Index), and perceived fatigue (assessed with the Pittsburgh<br /><br>Fatigability Scale).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary objectives are the capacity of the physiologic system to enhance<br /><br>homeostasis during illness is reflected by the capacity of different organ<br /><br>systems to restore deviating values back to normal values. Physiologic systems<br /><br>are expressed by cognitive, immunological, endocrine, musculoskeletal,<br /><br>cardiovascular, respiratory, and renal responses.<br /><br>Furthermore, age, sex, educationlevel, depression, comorbidity, medication,<br /><br>pain, in-hospital activity, and the capacity of the physiologic system to<br /><br>enhance homeostasis will be used in the analyses for the first secondary<br /><br>objective.<br /><br>Finally, in the qualitative interview, feasibility of an intervention to<br /><br>prevent hospital associated decline will be investigated. The use of a wearable<br /><br>(Fitbit) in combination with a digital application will be evaluated using two<br /><br>questions addressing user acceptability. </p><br>