Role of clomiphene citrate in infertile men with oligozoospermia
Not Applicable
- Conditions
- Health Condition 1: N461- Oligospermia
- Registration Number
- CTRI/2023/11/059791
- Lead Sponsor
- Dr Tejas Gundewar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Subfertile men with abnormal semen parameters.
2. Couples where female factor infertility has been ruled out.
3. Serum Testosterone level <300ng/dl.
4. Serum FSH/LH between 1.2 -10 IU/
Exclusion Criteria
EXCLUSION CRITERIA:
1. Baseline Serum Testosterone > 300 ng/dL.
2. Azoospermia.
3. Men with Hypergonadotropic hypogonadism (FSH >10IU/L, LH >10IU/L).
4. Men with Hypogonadotropic Hypogonadism (FSH 1.2 IU/L, LH<1.2IU/L).
5. Not willing to participate.
6. Varicocele has to be ruled out.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the effect of clomiphene citrate in improving sperm count in infertile men with oligospermia.Timepoint: Baseline and 12 weeks
- Secondary Outcome Measures
Name Time Method To study the pregnancy rates after treatment with clomiphene citrate. <br/ ><br>2. To study the effect of clomiphene citrate on progressive motility of sperms. <br/ ><br>3. To study the effect of clomiphene citrate on sperm morphology. <br/ ><br>4. To study the effect of clomiphene citrate on semen volume. <br/ ><br>5. To study the effect of clomiphene citrate on testicular size. <br/ ><br>6. To study the effect of clomiphene citrate on serum total testosterone levels.Timepoint: Baseline and 12 weeks