JPRN-jRCTs051230072
Recruiting
Phase 3
For postoperative body fluid management and postoperative complication prevention Torbaptan's effectiveness
Esaki Jiro0 sites200 target enrollmentJuly 20, 2023
ConditionsPatients receiving Open Heart Surgery
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Patients receiving Open Heart Surgery
- Sponsor
- Esaki Jiro
- Enrollment
- 200
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\) Patients planning to perform open heart surgery under a heart\-lung machine
- •2\) Patients who are aged 20 or older when acquiring consent
- •3\) Patients who have obtained document consent with their own freedom after fully understood participation in this research
Exclusion Criteria
- •1\)Patients who underwent emergency surgery
- •2\)Patients with a history of hypersensitivity to tolvaptan components or similar
- •compounds (such as mozavaptan hydrochloride)
- •3\)Patients receiving desmopressin acetate hydrate (nocturia due to nocturia in men)
- •4\)Patients with a history of hypersensitivity to sulfonamide derivatives
- •5\)Patients with heart failure and markedly decreased EF (EF\<30%)
- •6\)Patients with chronic renal dysfunction on dialysis
- •7\)Patients with liver cirrhosis
- •8\)Patients who underwent thoracoabdominal aortic replacement or heart\-beating coronary artery bypass surgery alone
- •9\)Patients who are already using tolvaptan including oral medicines and injections at
Outcomes
Primary Outcomes
Not specified
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