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MR Fingerprinting for Vestibular Schwannomas

Recruiting
Conditions
Vestibular Schwannoma
Registration Number
NCT04851925
Lead Sponsor
Medical University of Vienna
Brief Summary

MR Fingerprinting (MRF) will be performed in patients who will be treated with Gamma Knife radio surgery for a vestibular schwannoma before the intervention. Fifty patients will be included with a vestibular schwannoma of minimum 1cm in size. During follow-up, response of the tumor to radiosurgery will be evaluated for each patient with MRI. The aim of the study is to find patterns of vestibular schwannomas in MRF data which correlate with the type of response to radio surgery, i.e. tumor control after radiosurgery, further tumor growth despite radiosurgery, cystic transformation after radiosurgery.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
50
Inclusion Criteria

Planned Gamma Knife radiosurgery for vestibular schwannoma of minimum 1cm in size -

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Exclusion Criteria

Vestibular Schwannoma of less than 1cm in size. Other a priori treatment than Gamma Knife radiosurgery

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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Tumor growth3 years

Number of patients with growth of the tumor on follow-up MRI after radiosurgery

Tumor control3 years

Number of patients without further growth of the tumor on follow-up MRI after radiosurgery

Cystic transformation3 years

Number of patients with cystic transformation of the tumor on follow-up MRI after radiosurgery

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Medical University of Vienna

🇦🇹

Vienna, Austria

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