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Development of pharmacokinetic model for the target-concentration controlled infusion of cefazolin used as a prophylactic antibiotic in surgical patients

Not Applicable
Conditions
Diseases of the digestive system
Registration Number
KCT0005963
Lead Sponsor
Asan Medical Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot yet recruiting
Sex
All
Target Recruitment
40
Inclusion Criteria

? Patients over 20 to 80 years old
? Patients scheduled to undergo stomach or breast surgery at Asan Medical Center E rosette
? Patients with the physical status of the American Society of Anesthesiologists, Class 1-3
? Patients who weigh 40 kg or more
? Patients scheduled to receive cefazolin as a prophylactic antibiotic
? Patients who have agreed in writing to voluntarily participate in this clinical study

Exclusion Criteria

? Pregnant or breastfeeding women
? Patients with a history of hypersensitivity to cefazolin
? Patients with a history of cefazolin given within 3 days of the scheduled operation time
? Patients with hemoglobin <8 g/dl
? Estimated glomerular filtration rate measured before surgery <60 ml/min
? Patients who received other clinical trial drugs within 7 days of the surgery
? Patients deemed inappropriate by investigators

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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