KCT0004442
Completed
未知
Development of pharmacokinetic model for the target-concentration controlled infusion of cefoxitin used as a prophylactic antibiotic in surgical patients
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Asan Medical Center
- Enrollment
- 31
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •? Patients over 20 to 80 years old
- •? Patients scheduled to undergo colorectal or rectal surgery at Asan Medical Center
- •? Patients with physical status of the American Society of Anesthesiologists, Class 1\-3
- •? Patients who weigh 40 kg or more
- •? Patients scheduled to receive cefoxitin as a prophylactic antibiotic
- •? Patients who have agreed in writing to voluntarily participate in this clinical study
Exclusion Criteria
- •? Pregnant or breastfeeding women
- •? Patients with a history of hypersensitivity to cefoxitin
- •? Patients with a history of cefoxitin given within 3 days of the scheduled operation time
- •? Patients with hemoglobin \<8 g / dl
- •? Estimated glomerular filtration rate measured before surgery \<60 ml / min
- •? Patients who received other clinical trial drugs within 7 days of the surgery
- •? Patients deemed inappropriate by investigators
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Not Applicable
Development of pharmacokinetic model for the target-concentration controlled infusion of cefazolin used as a prophylactic antibiotic in surgical patientsDiseases of the digestive systemKCT0005963Asan Medical Center40
Completed
Not Applicable
Pharmacokinetic and pharmacodynamic modelling of routinely used off label drugs in premature neonates10039911Pijn en sedatiePrematurity10028971NL-OMON44214Erasmus MC, Universitair Medisch Centrum Rotterdam600
Active, not recruiting
Not Applicable
Dexmedetomidine PKPD and effect of stimulatioEUCTR2012-005443-24-NLMCG
Completed
Not Applicable
Development of a pharmacokinetic/pharmacodynamic model of dexmedetomidine, and the effect of repeated auditory stimulation on pharmacodynamics of dexmedetomidine.*gezonde vrijwilligers, dus geen aandoeningenpharmacodynamicPharmacokineticNL-OMON39625niversitair Medisch Centrum Groningen18
Not yet recruiting
Not Applicable
Study comparing anti-tuberculosis drug levels in saliva, plasma, and urine in patientsACTRN12623001088639Western Sydney Local Health District30