A clinical comparison of intrathecal morphine versus Erector spinae plane block for postoperative pain control in patients with End Stage Kidney Disease undergoing kidney Transplantation

Post operative pain is a major concern after any surgery.Inadequate control of pain after major surgeries continues to be a cause ofworry since it may be associated with a delay in recovery leading to anincrease in incidence of chronic post surgical pain. At present, there arenumerous methods exist for post operative pain management after major abdominalsurgeries such as intrathecal or intravenous(I.V)opioids, epidural analgesia,and ultrasound guided peripheral nerve blocks,however options for post‑kidneytransplantation analgesia are limited due to associated comorbidities in kidneytransplant recipients.Ultrasound guided regional anaesthesia is an upcoming and rapidly progressivemethod of pain management. The ultrasound guided erector spinae plane block(ESPB) is a newer regional anaesthesia technique  currently being explored as a viable optionfor analgesia. ESPB is performed by injecting local anaesthetic in the planebetween the erector spinae muscle and transverse process. Both intrathecalmorphine and ESPB has been investigated for use in post-operative analgesia forvarious surgeries like total abdominal hysterectomy, laparoscopiccholecystectomy, percutaneous nephrolithotomy, open nephrectomy, but there arevery limited studies in regarding there use in kidney transplant recepients. With the hypothesis that both intra-thecal morphine and ultrasoundguided ESPB has effect on post operative pain management So, this study isbeing planned to compare and evaluate both modalities and observe the duration, quality of analgesia and postoperative analgesic consumption in the patients undergoing kidneytransplantation.