Psychological, cognitive and neural factors associated with distinct profiles of mood change following the dissolution of a romantic relationship

Completed

Conditions: emotional state
mood
10027946

Registration Number: NL-OMON48640

Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 130

Inclusion Criteria

Age between 18 and 35 years
Caucasian ethnicity
Heterosexual
Right-handed
Dutch as a native language
Dissolution of a romantic relationship in the preceding two months at the time
of giving written informed consent
Relationship duration (prior to breakup) of at least six months

Exclusion Criteria

Presence of a neurological disorder (such as epilepsy)
Presence of a psychiatric disorder
Vision problems that cannot be corrected
(suspected) Pregnancy
Claustrophobia
MR incompatible implants or objects in the body
Tattoos containing pigments that form a safety risk
The refusal to be informed of structural abnormalities that could be detected
during the experiment

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study parameters are listed for each of our six objectives. (1) MDI<br /><br>scores, measured every two weeks (2) cognitive control ability, measured three<br /><br>times during the study (3) neural processing of reward and punishment during<br /><br>the Monetary Incentive Delay (MID) task in the fMRI scanner (4) brain activity<br /><br>and FC during resting-state fMRI scanning, (5) rumination scores and<br /><br>resting-state FC data (6) resting-state fMRI data collected both before and<br /><br>after the task-based fMRI scanning session.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcomes of objective 2 will be trait rumination and degree of<br /><br>neuroticism. The secondary outcome of objective 3 will be behavioral<br /><br>performance during the MID task. </p><br>