Romantic relationship breakup and mood changes
- Conditions
- mooddepressionheartbreakbreakupstemmingdepressieliefdesverdrietrelatieverbreking
- Registration Number
- NL-OMON25623
- Lead Sponsor
- niversity Medical Center Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- Not specified
- Target Recruitment
- 130
Inclusion Criteria
Age between 18 and 35 years
-Caucasian ethnicity
Exclusion Criteria
-Presence of a neurological disorder (such as epilepsy)
-Presence of a psychiatric disorder
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcomes are listed for each of our six objectives. (1) Major Depression Inventory (MDI) scores, measured every two weeks (2) cognitive control ability, measured three times during the study (3) neural processing of reward and punishment during the MID task in the fMRI scanner (4) brain activity and functional connectivity (FC) during resting-state fMRI scanning, (5) rumination scores and resting-state FC data (6) resting-state fMRI data collected both before and after the task-based fMRI scanning session.
- Secondary Outcome Measures
Name Time Method Secondary outcomes will be trait rumination, degree of neuroticism and behavioral performance during the MID task.