NCT02828345撤回不适用
Bio-marker Analysis Using Circulating Tumor Cells in Patients With Melanoma
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 主要终点
- Number of changes in CTC level from pre- to post-treatment
研究概览
简要总结
This research trial studies the levels of a type of biomarker, circulating tumor cells (CTCs), in the blood of patients with stage I-IV melanoma. A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Studying samples of blood in the laboratory obtained before and after treatment from patients with melanoma may help doctors learn more about changes that occur in CTC levels and whether they may predict how well patients will respond to therapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects must have signed tissue collection consent as described in protocol IRB# 703001,UPCC# 08607, PI: Giorgos Karakousis, MD
- •Subjects must be competent to consent for themselves.
- •Subjectsmust be adult (18 years or older).
- •Subjects must be initiating a new therapy for melanoma (so a pretreatment CTC count can be obtained).
排除标准
- •Children (less than 18yrs)
- •Patients in whom a pre-treatment CTC level cannot be obtained.
结局指标
主要结局
Number of changes in CTC level from pre- to post-treatment
时间窗: two years
次要结局
未报告次要终点
研究者
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