Cognitive Stimulation in patients with Parkinson's Disease Dementia (Train-ParC-D): Efficacy, prediction of response, and health-economic evaluation.
- Conditions
- F02.3Dementia in Parkinson disease
- Registration Number
- DRKS00010864
- Lead Sponsor
- Medizinische Psychologie | Neuropsychologie und Gender Studies & Centrum für Neuropsychologische Diagnostik und Intervention (CeNDI)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 82
Diagnosis of idiopathic Parkinson's disease (confirmed by a neurologist or psychiatrist);
- Parkinson's disease dementia according to Level-I-Diagnosis of the Movement Disorder Society Task Force (Dubois et al., 2007; Emre et al., 2007);
- Mild to moderate dementia operationalized with the help of the MMSE (range: 25 to 10 points);
- The patient is able to follow instructions;
- The patient is able to walk at least 10 meters without any help;
- Age: 50 to 85 years;
- German as native language or excellent German speaking skills;
- No/corrected visual or auditory impairments;
- Informed consent of a relative of the patient to complete external ratings of the patient as well as self-ratings.
- MMSE score above 25 points or below 10 points;
- Major depression (operationalized with the GDS > 10 points);
- Acute suicidality;
- Alcohol or drug abuse in the last three years;
- Severe neurological and/or psychiatric diseases with cognitive symptoms (acute or in the past; psychosis, epilepsy, stroke, traumatic brain injury, brain tumor);
- Further severe/life-threatening comorbidities which constitute an obstacle to the participation in a study.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cognition; time points of measurement: pre- and posttest and follow-up after 3 and 12 months; instruments used: CERAD-PLUS; digits backwards (Wechsler Memory Scale).
- Secondary Outcome Measures
Name Time Method