Clinical observation on the treatment of Parkinson's disease with fatigue by three injections
- Conditions
- Parkinson's disease fatigue
- Registration Number
- ITMCTR2200006777
- Lead Sponsor
- The First Affiliated Hospital of Guangzhou University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
? Meet the diagnostic criteria of PD (refer to the MDS: Clinical diagnostic criteria for Parkinson's Disease revised by the International Movement Disorders Association in 2015);
? Male or female, aged 35-75 years;
? Total score of Fatigue Severity Rating Scale (FSS) /9 >4
? Subjects should know the protocol and sign the informed consent.
?Patients with serious other systemic diseases, such as immune system diseases, endocrine system diseases (such as pheochromocytoma, hyperthyroidism, etc.), respiratory system diseases, cardiovascular and cerebrovascular diseases, or liver and kidney insufficiency.
(2) Clear can lead to Parkinson's syndrome or suspected symptoms related to other diseases, such as Parkinson's syndrome, senile tremor, etc.
?There was definite cerebellar ataxia or cerebellar eye movement abnormalities.
?There was definite loss of compound sensory cortex and motor apraxia or progressive aphasia.
?Downward vertical supranuclear gaze palsy or downward vertical saccade selective slowing.
?Parkinson-like symptoms that remain confined to the lower extremities three years after onset.
?Highly suspected behavioral variant frontotemporal dementia or primary progressive aphasia was diagnosed within 5 years of onset
?There was no significant therapeutic response to high-dose levodopa treatment.
?Patients with a clear history of mental illness or psychotic symptoms, such as depression, schizophrenia, etc.
?Have a history of substance abuse (such as alcohol, drugs, caffeine), sleeping pills or psychoactive drugs in the past six months.
?He or she participated in other clinical trials of drugs, acupuncture and moxibustion within one month before being enrolled in this study.
?Moxibushite.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Multidimensional Fatigue scale;
- Secondary Outcome Measures
Name Time Method Fatigue Severity Rating Scale;Parkinson's Disease Sleep Scale;Quality of life questionnaire for Parkinson's patients;Parkinson's Disease Fatigue Scale;Unified Parkinson's Disease Rating Scale Part 1;