Efficacy of Acupuncture vs sham acupuncture for Parkinson's disease anxiety: A randomized single blinded clinical trail

Phase 1

Recruiting

• Conditions: Parkinson's disease anxiety

• Registration Number: ITMCTR2100004940
• Lead Sponsor: The First Affiliated Hospital of Guangzhou University of Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1.Diagnosis of idiopathic Parkinsons disease;
2.Hoehn and Yahr staging scale stage 1 to 4;
3.HAMA scale score ranged from 14 to 29;
4.Able to provide written informed consent;
5.Men or women aged 35 to 80 years.

Exclusion Criteria

1.Significant neurologic, renal, cardiovascular or hepatic impairment;
2.Any disease can lead to Parkinsons syndrome or other conditions that are suspected to be related to the patients symptoms;
3.Significant cognitive impairment defined by MOCA < 23;
4.No significant response to high dose levodopa therapy;
5.Medical or psychiatric comorbidity that could compromise study participation;
6.Drug or alcohol use or dependence that could compromise study participation;
7.Exposure to study drug or acupuncture before 30 days of study entry;
8.Allergy or intolerance to acupuncture;
9.Subjects, who by investigators determination, will not be able to adhere to study protocol.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hamilton Anxiety Scale;

Secondary Outcome Measures

Name	Time	Method
Hydrocortisone;The new version of the Parkinson's Disease Comprehensive Assessment Scale of the World Society for Movement Disorders;adrenocorticotropic hormone;The Parkinson's Disease Questionnaire (PDQ-39):;