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Acupuncture in the treatment of Early-Onset Parkinson's Disease: A Prospective Randomized Controlled Clinical Study

Early Phase 1
Conditions
Early onset Parkinson's disease
Registration Number
ITMCTR2024000074
Lead Sponsor
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1.Meet the diagnostic criteria for Parkinson's disease;
2. Age 25-49 years;
3. Hoehn-Yahr stage 1-4;
4. Clear consciousness, stable vital signs, and able to communicate normally;
5. Willing to sign an informed consent form.

Exclusion Criteria

Patients will be excluded if they meet any of the following aspects:
1.Parkinsonism syndrome and Parkinson plus syndrome caused by cerebrovascular disease, poisoning and other causes;
2. Presence of serious diseases such as severe liver or kidney disease, blood disorders, tumors, endocrine diseases, or pain;
3. Concurrent participation in other drug and acupuncture clinical trials;
4. Communication barriers such as mental illness, hearing impairment, or cognitive impairment;
5. History of alcohol abuse or drug abuse;
6. Contraindications to acupuncture, such as ableeding tendency or local infection at acupoints;
7.Pregnant or planning to become pregnant.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
nified Parkinson's Disease Rating Scale;
Secondary Outcome Measures
NameTimeMethod
Proton magnetic resonance spectroscopy;Parkinson's Disease Daily Quality of Life-39 ;diffusion tensor imaging;Resting-state functional magnetic resonance imaging;Parkinson's disease non-motor Symptom Assessment Scale;Synapsys human posture balance system;musculoskeletal ultrasound;3D gait analysis;
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