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临床试验/NCT05681052
NCT05681052招募中不适用

Mottling Score and Central Venous Oxygen Saturation in Septic Shock Patients

Erzincan University1 个研究点 分布在 1 个国家目标入组 62 人开始时间: 2022年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
62
试验地点
1
主要终点
Difference in mottling score according to ScvO2 level during a septic shock.

研究概览

简要总结

Mottling score and central venous oxygen saturation are described as a clinical evaluation of tissue perfusion. This study describes mottling incidence and mottling score in septic shock patients according to central venous oxygen saturation.

详细描述

This study prospectively analyzed the data of patients admitted to our ICU between October 2022 to December 2022. All septic patients in whom the ScvO2 was measured and mottling scores were evaluated were included. This study enrolled patients aged ≥ 18 years in septic shock. Those excluded have peripheral arterial disease, black skin, cutaneous infection of the lower limbs, pregnancy, and relative refusal. The characteristics of patients were recorded at admission (H0), including demographics (age, sex, body mass index (BMI), admission the Acute Physiology and Chronic Health Evaluation (APACHE II) score, Glasgow Coma Scale (GCS) and sequential organ failure assessment (SOFA) score. Variables such as plasma lactate level, daily urine output, plasma creatinine level, the ratio of arterial oxygen pressure related to inspired oxygen fraction (PaO2/FiO2), hemoglobin level, heart rate, mean arterial pressure, pulsatile saturation in oxygen (SpO2) and body temperature were recorded at H0 and 6 hours after initial resuscitation (H6).

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients aged ≥ 18 years in septic shock.

排除标准

  • patients having the peripheral arterial disease
  • black skin,
  • cutaneous infection of the lower limbs
  • pregnancy
  • relative refusal

结局指标

主要结局

Difference in mottling score according to ScvO2 level during a septic shock.

时间窗: at 0th hour, admission; at 6th hour after initial treatment

0 score is minimum level, meaning no mottling, meaning better outcome 5 score is maximum level, meaning more mottling, meaning worse outcome

Difference in mottling incidence according to ScvO2 level during a septic shock.

时间窗: at 0th hour, admission; at 6th hour after initial treatment

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nurcan Kutluer Karaca

Asistant Profesor

Erzincan University

研究点 (1)

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