Investigating the effect of pomegranate skin mouthwash on oral hygiene and bacterial colonization of oral and tracheal intubated patients admitted to the intensive care units(ICUs)

Phase 1

Recruiting

Conditions: Investigating the effect of pomegranate peel extract mouthwash on oral hygiene.

Registration Number: IRCT20230513058170N1

Lead Sponsor: Zahedan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 80

Inclusion Criteria

Intubated patients admitted to the special care department of teaching hospitals in Zahedan
- Patients with a tracheal tube and a level of consciousness of 3 to 7 on the GCS scale
2- Age 18 to 65 years
3- 24 hours have passed since the admission or hospitalization of the patient
4- Having natural teeth in the patient
5- Not having a history of allergy to pomegranate
6- Absence of a specific lesion in the mouth
7- The patient should not have radiotherapy experience
8- Willingness of the patient's legal guardian to continue participating in the study
9- Obtaining oral health evaluation checklist score less than 16.

Exclusion Criteria

- Airway damage during intubation
2- Pneumonia as an inpatient diagnosis
3- History of allergy to used mouthwash, asthma, allergic rhinitis and skin inflammation
4- Signs of sensitivity to mouthwash, such as redness, urticaria, and sores inside the mouth
5- Transfer of the patient from ICU or his death before the completion of the research

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The bacterial colonization status of the tracheal tube of intubated patients. Timepoint: on the first day (before admission of patients) and on the fourth day in the ICU department. Method of measurement: Beck's measurement scale - oral mucosal plaque score - culture from Score obtained from the scale (MPS) = 2-4 a unacceptable MPS = 7-8 weak, the score received every day on the scale (BOAS). Number 5 no disorder, 6-10 mild disorder, 11-15 moderate disorder, 16-20 severe disorde?Cultivation on the first day (before admission of patients) and the fourth day in the ICU departmentmouth and tracheal tube.

Secondary Outcome Measures