Dynamic MRI with mapping of T1-values as indicators of disease activity in luminal Crohn’s disease.
Completed
- Conditions
- Crohn's disease, ziekte van Crohn
- Registration Number
- NL-OMON21489
- Lead Sponsor
- Academic Medical Center, department of radiology
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
1. Proven Crohn’s disease (by endoscopy or histopathology);
2. Scheduled to undergo an ileocolonoscopy as part of their clinical follow-up;
Exclusion Criteria
1. Under 18 years of age;
2. General contraindications to MRI (claustrophobia, pregnancy, renal insufficiency, pacemakers).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main study parameter will be the accuracy of detecting disease activity and efficacy of DCE MRI with T1 mapping at MR in patients with proven Crohn’s disease as compared to ileocolonoscopy with histopathology.
- Secondary Outcome Measures
Name Time Method The secondary endpoints will be the comparison of DCE MRI with T1-mapping as compared to CDEIS, CRP, CDAI.