Comparing the relaxation effect of diazepam of oral administration of single and divided dose in Patients with limited mouth opening origin of masticatory muscles
Not Applicable
Recruiting
- Conditions
- limitation of mouth opening due to masticatory muscles.Diseases of the musculoskeletal system and connective tissue
- Registration Number
- IRCT2017032933167N1
- Lead Sponsor
- Vice Chancellor Of Research, Mashhad University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
Exclusion criteria:Pregnancy:Breastfeeding;using Drugs have interactions with diazepam (such as cimetidine, Amvprazvl, phenytoin, erythromycin and fungicides);Liver and kidney disfunctions (with tests SGOT, SGPT, ALP, Bun-Creatinine); alcoholism; glaucoma; severe difficulty breathing; Sleep Apnea; Epilepsy;Consumers of other benzodiazepines; other muscle relaxants and anti-inflammatory drugs; close lock; the joint disorders; chronic slow mandible; patients with submucosal fibrosis; patients radiotherapy; Sensitivity to diazepam
;Patients with limitation in mouth opening by the source of masticatory muscle
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Range of mouth opening. Timepoint: before Intervention and in 3,5 and 7 days after Intervention. Method of measurement: the distance between inscisal edge of two right centrals in milimeter.
- Secondary Outcome Measures
Name Time Method Pain through opening. Timepoint: before Intervention and in 3,5 and 7 days after Intervention. Method of measurement: VAS(visual analog scale).;Drug complications. Timepoint: before Intervention and in 3,5 and 7 days after Intervention. Method of measurement: patient's discription.