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Glu-COACH: a Peer-mentoring Intervention to Reduce Disparities in Continuous Glucose Monitor (CGM) Use

Not Applicable
Recruiting
Conditions
Type 1 Diabetes
Interventions
Behavioral: Enhanced standard-of-care (ESOC)
Behavioral: Glu-COACH
Registration Number
NCT06171412
Lead Sponsor
Yale University
Brief Summary

This is a study to develop and evaluate a peer mentoring intervention for Black and Latinx adolescents with type 1 diabetes to increase the initiation and maintenance of a continuous glucose monitoring (CGM) device. This device is a standard of care to improve diabetes management related to diet, exercise, and insulin. Use of CGM has been shown to improve health outcomes, but is not used by adolescents of color. Peer mentors may help improve usage.

Detailed Description

In Phase 1, investigators developed the intervention with a stakeholder advisory group. In Phase 2, investigators will conduct a small clinical trial to evaluate the intervention. Phase 1 is complete with the focus of this registration being Phase 2, the clinical trial.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Diagnosis of type 1 diabetes, as determined clinically by the presence of ketosis or ketoacidosis at presentation and/or the presence of at least one diabetes-related auto-antibody
  • Self-identification as Black and/or Latinx.
  • Ability of participant to comprehend and communicate in written and spoken English, in order to complete surveys and participate in mentioning sessions and other interview (parents/caregivers do not need to have English fluency)
  • Access to personal cellphone or tablet to participate in remote video sessions with the peer mentor
  • Naïve to or not currently using CGM. "Current" use is defined as any CGM used for clinical management of T1D for > 1 week within the last three months.
Exclusion Criteria
  • Participants with a prior severe skin reaction to CGM sensor or adhesive.
  • Current use of CGM
  • Current or planned pregnancy
  • Inability to comprehend or communicate in spoken/written English
  • Subjects with other medical or mental health conditions that would, in the opinion of the investigators, interfere with the conduct of the study or present additional risk to the individual.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Enhanced standard-of-care (ESOC)Enhanced standard-of-care (ESOC)This group will receive ESOC including additional training and support on CGM beyond routine clinical practice.
Glu-COACHEnhanced standard-of-care (ESOC)The experimental group will receive ESOC plus peer-mentoring support from a peer of the same cultural identity (Glu-COACH) and access to a private social media group for all Black and Latinx teens to improve the initiation and maintenance of CGM (Dexcom)
Glu-COACHGlu-COACHThe experimental group will receive ESOC plus peer-mentoring support from a peer of the same cultural identity (Glu-COACH) and access to a private social media group for all Black and Latinx teens to improve the initiation and maintenance of CGM (Dexcom)
Primary Outcome Measures
NameTimeMethod
Mean hours per week CGM worn3 months and 6 months

Mean hours per week of documented CGM wear. This will be documented through the CGM program. The primary analysis will be CGM use time at 6 months between the two groups.

Secondary Outcome Measures
NameTimeMethod
CGM Mean glucosebaseline, 3 months and 6 months

The mean glucose in mg/dL

CGM Percentage time in range (70-180mg/dL)baseline, 3 months and 6 months

Percentage of time participants glucose values are in the target range of 70-180 mg/dL

Number of Adverse diabetes-related events (severe hypoglycemia)baseline, 3 months and 6 months

Number of Yes/no responses via self report of severe hypoglycemia

Mean score in Diabetes Distress using Problem Areas in Diabetes-Teen (PAID-T) surveybaseline, 3 months and 6 months

PAID-T is a 26 item survey that measures of diabetes-specific distress for teenagers with type 1 diabetes. Items are rated on a 6-point Likert scale: 1-2, not a problem; 3-4, a moderate problem; or 5-6, a serious problem. Item scores are summed to form a total score (range 26-156), with higher scores indicating greater distress.

Mean score Diabetes self-efficacy using Diabetes Management Self-Efficacy scale (DMSES)baseline, 3 months and 6 months

Measures the diabetic patients confidence regarding diet, exercise and medical treatment. It is a 20 item survey. Responses are rated on a 5 point scale ranging from 1- ''can't do at all'' to 5- ''certain can do''. Item scores are summed to form a total score range 0-100 with higher scores indicating higher self-efficacy in performing diabetes self management activities.

Mean score Family conflict using Diabetes Family Conflict Scale (DFCS)baseline, 3 months and 6 months

DFCS is a 19-item measure of diabetes management and the implications it has on the caregiver-child relationship. Items are scored on a 3-point Likert scale (1 = never argue, 2 = sometimes argue, and 3 = always argue). Item scores are summed with a total scale range of 19 to 57 with higher scores indicating a higher level of conflict.

Mean A1C concentrationbaseline, 3 months and 6 months

Mean A1C concentration

Mean score Benefits and burdens of CGM usebaseline, 3 months and 6 months

This survey consists of two sub-scales (one is benefits, one is burdens) with 8 items each. Each item scored Likert scale - Scored 1-5 Strongly Disagree to Agree. Items summed and divided by # of items. Mean score across participants. Each subscale range 1-5, with 5 indicating greater perceived benefits or burdens.

Number of Adverse diabetes-related events (diabetic ketoacidosis)baseline, 3 months and 6 months

Number of Yes/no responses via self report of diabetic ketoacidosis

Mean score Depressive symptoms using Patient Health Questionnaire-2 (PHQ-2)baseline, 3 months and 6 months

The PHQ-2 is a 2 item questionnaire used to assess the frequency of depressed mood. Item scores are summed with a total score ranging from 0 to 6 with higher scores indicating higher frequency of depressed moods.

Mean score Glu-Coach satisfaction scale3 months and 6 months

5 items scored on a Likert scale, scored 1-5 (not at all to extremely). Items summed and divided by # of items. Mean score across participants. Score range 1-5, with 5 indicating greater satisfaction.

Mean score Anxiety symptoms using General Anxiety Disorder-7 (GAD-7)baseline, 3 months and 6 months

General Anxiety Disorder- 7 (GAD-7) is a 7 item self report instrument that measures anxiety. Items are scored on a 4-point scale, ranging from "not at all (0)" to "nearly everyday (3)". Item scores are summed with a total score ranging from 0 to 21: 0-4 Minimal anxiety; 5-9 Mild anxiety; 10-14 Moderate anxiety; 15-21 Severe anxiety.

Mean Score Technology Attitudesbaseline, 3 months and 6 months

5 items scored on a Likert scale, scored 1-5 (strongly disagree to agree). Items summed and divided by # of items. Mean score across participants. Score range 1-5, with 5 indicating more positive attitude about technology.

Mean count Barriers to Device Use3 months and 6 months

19 items with yes/no response. Mean number of barriers across participants. Higher value indicates more barriers.

Trial Locations

Locations (1)

Yale Children's Diabetes Clinic

🇺🇸

New Haven, Connecticut, United States

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