MedPath

JOHN HOPE FRANKLIN CENTER

JOHN HOPE FRANKLIN CENTER logo
🇺🇸United States
Ownership
Private
Established
1838-01-01
Employees
5K
Market Cap
-
Website
http://www.duke.edu

Clinical Trials

2.0k

Active:65
Completed:1320

Trial Phases

6 Phases

Early Phase 1:17
Phase 1:130
Phase 2:201
+3 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (1568 trials with phase data)• Click on a phase to view related trials

Not Applicable
1029 (65.6%)
Phase 2
201 (12.8%)
Phase 4
151 (9.6%)
Phase 1
130 (8.3%)
Phase 3
40 (2.6%)
Early Phase 1
17 (1.1%)

Cognitive Rehabilitation for Treatment of Anger in Veterans With TBI and PTSD

Not Applicable
Not yet recruiting
Conditions
Traumatic Brain Injury (TBI)
Posttraumatic Stress Disorder (PTSD)
First Posted Date
2025-11-13
Last Posted Date
2025-11-13
Lead Sponsor
Duke University
Target Recruit Count
100
Registration Number
NCT07227987
Locations
🇺🇸

Duke University School of Medicine, Durham, North Carolina, United States

ESP Blocks for Posterior Spinal Fusion

Not Applicable
Not yet recruiting
Conditions
Postoperative Pain
Interventions
Drug: ESP Block with Bupivacaine + Liposomal Bupivacaine
Drug: ESP Block with Bupivacaine
First Posted Date
2025-11-13
Last Posted Date
2025-11-13
Lead Sponsor
Duke University
Target Recruit Count
75
Registration Number
NCT07228039
Locations
🇺🇸

Duke University, Durham, North Carolina, United States

PrEP (Pre-exposure Prophylaxis) Stigma and Women Ethnodrama Pilot Phase

Not Applicable
Recruiting
Conditions
HIV
First Posted Date
2025-11-10
Last Posted Date
2025-11-10
Lead Sponsor
Duke University
Target Recruit Count
160
Registration Number
NCT07225894
Locations
🇰🇪

Impact Research and Development, Kisumu, Kenya

Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization

Not Applicable
Not yet recruiting
Conditions
Stroke
Arm Weakness as a Consequence of Stroke
Upper Extremity Hemiparesis
Upper Extremity Impairments
Upper Extremity Weakness
First Posted Date
2025-10-23
Last Posted Date
2025-10-23
Lead Sponsor
Duke University
Target Recruit Count
24
Registration Number
NCT07220005
Locations
🇺🇸

Duke University Hospital, Durham, North Carolina, United States

Compact Auto-Aligning Multi-Modal Eye Imaging to Diagnose Traumatic Eye Injury

Not yet recruiting
Conditions
Ocular Pathologies
First Posted Date
2025-10-20
Last Posted Date
2025-10-20
Lead Sponsor
Duke University
Target Recruit Count
70
Registration Number
NCT07218835
Locations
🇺🇸

Duke Eye Center, Durham, North Carolina, United States

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News

Gates Foundation Awards $13.5 Million to Slash Monoclonal Antibody Costs from $100 to $10 Per Gram

The Gates Foundation has awarded $13.5 million across multiple projects to reduce monoclonal antibody manufacturing costs from the current $50-100 per gram to just $10 per gram, making these life-saving treatments accessible in low-resource settings.

Pharming Group to Present 12 Studies on Rare Disease Treatments at 2025 ACAAI Meeting

Pharming Group will present 12 accepted abstracts at the 2025 ACAAI Annual Scientific Meeting in Orlando, showcasing new clinical and economic data for their rare disease portfolio.

NeOnc Technologies Strengthens Scientific Advisory Board with Two Leading Duke Neuro-Oncologists

NeOnc Technologies has appointed two distinguished Duke University neuro-oncologists, Dr. David M. Ashley and Dr. Henry S. Friedman, to its scientific advisory board to guide development of CNS cancer therapies.

Duke Engineers Develop AI-Powered Platform to Optimize Nanoparticle Drug Delivery

Duke University biomedical engineers have created TuNa-AI, an artificial intelligence platform that combines automated wet lab techniques to design optimized nanoparticles for drug delivery applications.

Engineered CD40 Antibody Achieves Complete Cancer Remission in Phase 1 Trial

A modified CD40 agonist antibody called 2141-V11 demonstrated remarkable efficacy in a phase 1 clinical trial, with six of 12 patients experiencing significant tumor reduction and two achieving complete remission.

NeOnc Technologies Receives FDA Authorization for Phase II Brain Cancer Trial of NEO212

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Dual Clinical Trials Advance Mesothelioma Treatment with Novel Immunotherapy Combinations

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Agenus Advances BOT/BAL Combination Therapy with Phase 3 BATTMAN Trial Launch for Metastatic Colorectal Cancer

Agenus announced the launch of the BATTMAN Phase 3 trial evaluating botensilimab (BOT) and balstilimab (BAL) combination therapy in metastatic microsatellite stable colorectal cancer patients who have exhausted treatment options.

UroMems Receives FDA and ANSM Clearance for Pivotal Trial of Smart Artificial Urinary Sphincter

UroMems received investigational device exemption approval from the FDA and French ANSM to begin the SOPHIA2 pivotal trial of its UroActive smart implant for treating male stress urinary incontinence.

Fifty1 AI Labs Completes Landmark Phase III REVIVE Trial for Long COVID Treatment

Fifty1 AI Labs successfully completed the REVIVE Adaptive Platform Trial, the largest and most rigorous Long COVID study to date, enrolling over 600 participants across multiple global sites.

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