French and EuRopean Outcome Registry in Intensive Care Unit
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Intensive Care Unit Syndrome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
- Enrollment
- 2137
- Locations
- 2
- Primary Endpoint
- All cause mortality at one year after ICU discharge
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
The purpose of this study is to identify within a cohort of ICU patients admitted for severe illness those who are at risk of death in the year following the discharge from ICU.
Detailed Description
FROG-ICU is an epidemiological, observational, prospective, multi centric, cohort study designed for description, prognostic and evaluation. This trial includes as a first step a complete registry of patients admitted to the ICU and as a second step, the outcome of the patients at 1 year after they have been discharged alive from ICU. Plasma and urine samples will be with drawn biomarkers measurements at admission and ICU discharge. It is a multicentric study involving 1 center in Belgium et 24 centers in France.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •age \< 18 years
- •pregnancy women
- •Breast-feeding women
- •Not affiliated with social security
- •Dying man
- •End of life patient
- •Traumatic Brain Injury (IGCS \< 8)
- •vegetative coma
- •Transplanted for less than year
- •no french speaking patient
Outcomes
Primary Outcomes
All cause mortality at one year after ICU discharge
Time Frame: one year
Secondary Outcomes
- To identify key determinants of cardiovascular morbidity and mortality in the year following a stay in ICU(one year)
- To investigate the performance of plasma biomarkers usually measured in ICU, to assess the risk of death during the stay in ICU and one year after the discharge.(one year)
- To set up a biological collection of plasma and urine, in order to measure new plasma biomarkers in the assessment of prognosis in the year following a stay in ICU.(one year)
- To assess quality of life in the year following a stay in ICU(one year)
- to evaluate social conditions(one year)