The Influence of Oxytocin on Automatic Imitation Behaviour in Healthy Adults
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To evaluate the automatic imitation behaviour 45 minutes after drug administration
研究概览
简要总结
In this study, the influence of oxytocin on automatic imitation behaviour is investigated. Healthy adults will be administered with either oxytocin or a placebo, and will perform an imitation-inhibition task (as a measure of automatic imitation behaviour). To determine the specificity of the oxytocin effect, an unrelated cognitive task (Stroop task) will also be presented.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •non-smoker
排除标准
- •no pacemaker, deep brain stimulation electrodes or other stimulation devices
- •normal neurological history (no brain operations, migraine, epilepsy, alcoholism
- •no epilepsy in family
- •no chronic disease(s) that require constant medication (asthma, hypertension, diabetes)
- •no medication 24h prior to experiment
- •no alcohol or caffeine 2h prior to experiment
- •no sleep deprivation 24h prior to experiment
研究组 & 干预措施
Sea water
Sea water 3 puffs per nostril
干预措施: Sea water (Drug)
Oxytocin
Oxytocin 24 IU (3 puffs) per nostril
干预措施: Oxytocin (Drug)
结局指标
主要结局
To evaluate the automatic imitation behaviour 45 minutes after drug administration
时间窗: 120 minutes
Since the effects of oxytocin are only visible after 45 minutes, participants will have to wait 45 minutes before starting the experimental tasks. In the meantime, they will be given an unrelated cognitive-emotional filler task which will last ± 30 minutes. Afterwards, they will perform two experimental tasks: an imitation-inhibition task and a cognitive control task (Stroop task).
次要结局
未报告次要终点