Metformin is more effective than insulin in treating gestational diabetes

Phase 2

• Conditions: gestational diabetes.; Diabetes mellitus in pregnancy, unspecified

• Registration Number: IRCT2014010116025N1
• Lead Sponsor: Vice Chancellor for Research and Technology, Hormozgan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 400

Inclusion Criteria

age ranging from 18 to 45; affliction with gestational diabetes according to the criteria pinpointed by Australian Diabetes in Pregnancy Society (ADIPS); pregnancy with a single embryo; 20th to 32th week of pregnancy; meeting the hospital’s common criteria concerning the beginning of insulin (after the diet intervention and physical exercises their capillary blood glucose after an overnight fast should be above 90 mg/dl or their 2hpp blood glucose measurement should be above 120.6 d.l.). Exclusion criteria: pre-pregnancy diabetes; metformin consumption; embryonic anomaly; hypertensive pregnancy disorders; pre-eclampsia; embryonic growth restriction and premature rupture.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Maternal blood glucose control. Timepoint: During pregnancy: every 2 weeks. Method of measurement: During pregnancy: every 2 weeks.

Secondary Outcome Measures

Name	Time	Method
Birth weight. Timepoint: 2 hour after delivery. Method of measurement: Neonatal weight measurement.;Birth height. Timepoint: 2 hour after delivery. Method of measurement: Baby Height gauges.;Head circumference. Timepoint: 2 hour after delivery. Method of measurement: With using meter.;Chest circumference. Timepoint: 2 hour after delivery. Method of measurement: With using meter.;First minute apgar. Timepoint: One minute after delivery. Method of measurement: Apgar score.;Fiftt minute apgar. Timepoint: Five minutes after delivery. Method of measurement: Apgar score.