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Effect of Perioperative Dexmedetomidine Administration on Outcome in Cardiac Surgery Patients

Phase 4
Completed
Conditions
Patient Outcome Assessment
Interventions
Registration Number
NCT03091166
Lead Sponsor
Moscow Regional Research and Clinical Institute (MONIKI)
Brief Summary

Investigation of effect of perioperative Dexmedetomedine administration on mortality, length of ICU and hospital stay, delirium onset, major adverse cardiac and cerebrovascular events, acute kidney injury in cardiac surgery patients.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
169
Inclusion Criteria
  • Written informed agreement
  • Elective surgery
  • Use of CPB
Read More
Exclusion Criteria
  • Previous prolonged immobilization
  • Reoperation
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
DexmedetomidineDexmedetomidine-
Primary Outcome Measures
NameTimeMethod
30DM30 days after surgery

30-day mortality

Delirium30 days after surgery

Postoperative delirium

Secondary Outcome Measures
NameTimeMethod
VIS5 days after surgery

Vasoactive- Inotropic Score

AKI7 days after surgery

Acute kidney injury

Subsyndromal delirium30 days after surgery

Subsyndromal postoperative delirium

ICU-LOS7 days after surgery

Length of ICU stay

H-LOS30 days after surgery

Hospital length of stay

MACCE30 days after surgery

Major adverse cardiac and cerebrovascular events

Trial Locations

Locations (1)

Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy

🇷🇺

Moscow, Russian Federation

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