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AI-Enhanced Restoration of Brain PET/CT Images with Reduced Radiotracer Injection Doses

Not Applicable
Conditions
Mental and behavioural disorders
Registration Number
KCT0009640
Lead Sponsor
Yonsei University Health System, Severance Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot yet recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

1. Adults aged 60 and older, both male and female.
2. Capable of communicating in Korean and sufficiently understanding and consenting to the purpose and process of the research.
3. Patients who, in the judgment of the examiner, have adequate vision, hearing, language ability, motor function, and comprehension to follow the testing procedures (use of aids such as glasses, hearing aids, etc., is allowed).
4. Patients with the cognitive ability to make voluntary decisions about participating in the research.

Exclusion Criteria

1. Individuals suspected of having other causes of cognitive impairment such as neurosyphilis, hypo/hyper-thyroidism, metabolic encephalopathy, brain tumor, acute cerebral hemorrhage, acute cerebral infarction, Wernicke’s encephalopathy, based on hematologic tests and brain magnetic resonance imaging conducted within the last 6 months.
2. Patients without brain magnetic resonance imaging.
3. Employees directly involved in this clinical study or their immediate family members for whom voluntary participation is deemed difficult.

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The statistical difference in Standardized Uptake Value Ratio (SUVR) between images acquired with reduced radiotracer injection dose and those acquired with the original count.
Secondary Outcome Measures
NameTimeMethod
The image parameters (PSNR, SSIM, NRMSE) and visual analysis between images acquired with reduced radiotracer injection dose and those acquired with the original count.
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