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PET scan imaging for recording brain activity in cochlear implant recipients with tinnitus

Completed
Conditions
noise in the head
tinnitus
10022396
10042258
Registration Number
NL-OMON34253
Lead Sponsor
niversitair Medisch Centrum Groningen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

10 healthy one-sided cochlear implant recipients who experience inhibition of their chronic tinnitus (> 3 months, perceived in the head, constant in presence)by turning the cochlear implant on, age > 18, right handed.
10 healthy one-sided cochlear recipients who do not experience inhibition of their chronic tinnitus (> 3 months, perceived in the head, constant in presence) by the cochlear implant, age >18, right handed.

Exclusion Criteria

Presence of any major medical, neurological or psychiatric diagnoses now or in the past, specific epilepsy, severe head injury or previous cranial neurosurgery, participation in a study with radiation exposure in the year prior to this study, radiological workers, use of drugs or medications that reduce cortical excitation such as anticonvulsants, benzodiazepines or other sedatives (e.g. antihistamines), pregnancy.

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The main outcome measure will be the change in cortical activity in cochlear<br /><br>implant recipients who experience subjective improvement of tinnitus by turning<br /><br>the cochlear implant on compared to cochlear implant recipients who do not<br /><br>experience improvement of tinnitus by turning the cochlear implant on. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Not applicable.</p><br>
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