Clinical Trials/IRCT20200907048646N1

IRCT20200907048646N1

Recruiting

Phase 3

Evaluation of the effect of carvedilol in the prevention of cardiovascular complications induced by (5fu (5Fluorouracil) therapy in gastrointestinal cancer (GI) patients

Ardabil University of Medical Sciences0 sites60 target enrollmentTBD

ConditionsGastrointestinal cancers (Esophageal cancer, Gastric cancer, Pancreatic cancer, Colon cancer).Malignant neoplasm of stomach

Overview

Phase: Phase 3
Intervention: Not specified
Conditions: Gastrointestinal cancers (Esophageal cancer, Gastric cancer, Pancreatic cancer, Colon cancer).
Sponsor: Ardabil University of Medical Sciences
Enrollment: 60
Status: Recruiting
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

No summary available.

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

5 years ago

Study Type

Interventional

Sex

All

Investigators

Sponsor

Ardabil University of Medical Sciences

Eligibility Criteria

Inclusion Criteria

•All gastrointestinal cancer patients in the age range of 18 to 80 years old underwent 5FU therapy.
•LVEF (left ventricular Ejection Fraction)\>50%

Exclusion Criteria

•Patients with IHD (history of PCI, CABG, and Plavix consumption )
•Mitral stenosis and cardiomyopathy
•ECG changes characteristic to ischemia (ST\-elevation more than 0\.5mm and ST\-depression more than 1 mm)
•Acute myocardial ischemia at any stage of the study (ECG changes characteristic to ischemia, increased cardiac enzymes, or ischemic manifestations on echocardiography).

Outcomes

Primary Outcomes

Not specified

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