IRCT20190628044046N1招募中3 期
Determining the Preventive Effect of Carvedilol on Reducing Transtosomab Cardiac Complications in Patients With Early Stages of HER2-Breast Cancer
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- no limit 至 no limit（—）
- 性别
- All
入选标准
- •Patients who have recently been diagnosed with breast cancer (HER2-overexpressing) (stage I to IIIA) and are candidates for adjuvant treatment with trastuzumab.
- •The ability to have an informed consent.
排除标准
- •Left Ventricular Ejection Fraction (LVEF) baseline less than 50%, history of heart failure.
- •Contraindication of treatment with or receiving drugs for beta blocker(BB).
- •cardiomyopathy or valvular heart disease, myocardial infarction, uncontrolled blood pressure.
- •history of radiotherapy or chest chemotherapy to the chest.
- •filtration Glomerular volume 30 mL / min / 1.73 m2, which is calculated using the Modification of Diet in Renal Disease (MDRD)method.
研究者
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