earning, Memory and Networks in the Human Brain: Single Neuron Recordings in Depth-electrode Candidates for Epilepsy Surgery

Completed

• Conditions: epilepsy; seizures; 10029209; 10039911

• Registration Number: NL-OMON38351
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

Epilepsy patients with macroelectrode and microwire implants. No specific inclusion criteria for the study population apply additional to the standard clinical criteria for the indication of depth electrodes, other than written informed consent.

Exclusion Criteria

Hypertension in the medical history of the patient or the use of anti-hypertensive medication.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are the macro- and microelectrode recordings,<br /><br>assessing functional connectivity (SL and PLI) and neuronal brain networks<br /><br>(cluster coefficient and path length), seizure frequency and epilepsy burden.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>These includes the test results of the patients memory and attention tests. </p><br>