Single neuron characteristics in epilepsy surgery candidates.
- Conditions
- single neuronepilepsyseizurestemporal lobeneural networksfunctional connectivitygraph theorymemoryattention
- Registration Number
- NL-OMON28961
- Lead Sponsor
- Prof. Dr J.J. Heimans, neurologist, head of the Department of NeurologyVU University Medical CentrePO Box 70571007 MB AmsterdamThe NetherlandsT +31 20 4442821F +31 20 4442800Email: JJ.Heimans@vumc.nl
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
Epilepsy patients with macroelectrode and microwire implants. No specific inclusion criteria for the study population apply additional to the standard clinical criteria for the indication of depth macroelectrodes, other than written informed consent.
Exclusion Criteria
Patients with a history of hypertension, or patients who are using anti-hypertensive medication at time of evaluation for this study, will be excluded from this study.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main study parameters are the macro- and microelectrode recordings, assessing functional connectivity (SL and PLI) and neuronal brain networks (cluster coefficient and path length), seizure frequency and epilepsy burden.
- Secondary Outcome Measures
Name Time Method These includes test results of the patients memory and attention tests.