Recognition of Sleep Apnea by Analysis of the Routine Holter ECG - Pilot Study with Exploratory Data Analysis

Recruiting

• Conditions: G47.3; R06.3; Periodic breathing; Extreme obesity with alveolar hypoventilation; E66.2; Sleep apnoea

• Registration Number: DRKS00008567
• Lead Sponsor: Medizinische Klinik (Krehl-Klinik), Abteilung Innere Medizin III (Kardiologie, Angiologie und Pneumologie)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-09-03
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Patients who are scheduled for a Holter ECG registration by the Heidelberg University Hospital. Patients must be able to attach polygraphy sensors and activate the pholygraphy device.

Exclusion Criteria

none

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The reference value for the severity of a sleep related breathing disorder will be the apnea-hypopnea index (AHI) as assessed from the polygraphy. An exploratory data analysis will identify the suitability of ECG parameters for robust detection of sleep apnea, and the level of sensitivity and specficity that can be expected from analysis of routine Holter ECG recordings. Moreover, the prevalence of sleep apnea in a routine Holter ECG collective will be estimated.<br>

Secondary Outcome Measures

Name	Time	Method
The possibility to specifically identify respiratory events of central origin from the routine Holter ECG, and the impact of concomitant factors like comorbidity or medication on the detectability of sleep related breathing disorders from the Holter ECG <br>